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I am getting real fed up with these children not understanding how to use google stating that these are unique medications.
**First lets examine metabolites:**
[In vitro metabolic fate of nine LSD-based new psychoactive substances and their analytical detectability in different urinary screening procedures.](https://www.ncbi.nlm.nih.gov/pubmed/30617391)
>Total, N-dealkylation and hydroxylation, in addition to mixtures of those steps mostly catalyzed by CYP1A2 and CYP3A4, were discovered. To get ALD-52, 1P-LSD, and 1B-LSD, deacylation to LSD has been detected.
There does appear to be a scarcity of information on the pharmacokinetics, but it’s clear it’s metabolised to LSD.
**However, how does it really compare to LSD? **
[Return of the lysergamides. Part I: Analytical and behavioral characterization of 1-propionyl-d-lysergic acid diethylamide (1P-LSD)](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829483/)
It had been discovered that 1P-LSD generated a dose-dependent growth in HTR counts, which it’d ~38percent (ED50 = 349.6 nmol/kg) of this effectiveness of LSD (ED50 = 132.8 nmol/kg). What’s more, the HTR was abolished when 1P-LSD government followed pre-treatment using the discerning 5-HT2A receptor antagonist M100907 (0.1 mg/kg, SC), which affirms that the behavioral reaction is mediated by activation of this 5-HT2A receptor. These results imply that 1P-LSD generates LSD-like consequences in mice, consistent with its classification as a serotonergic hallucinogen. Nonetheless, the degree to which 1P-LSD may reveal side effects in humans like LSD remains to be researched.
This lack of effectiveness is to be anticipated with an expert drug
**Psychedelics are different each time**
That is something I do not have a supply for, but I really don’t think that it’s needed. In the event you should take 3.5 g of mushrooms now, then 1 year from today, you take 3.5 g, the excursions can be wholly different from one another. This large part has to do with how psychedelics work out from your sense at the moment and in which you are in life then.
In summary, google until you inquire, and quit indicating that both of these medications are indeed distinct from one another when the differences are second.